The Ishkashim district is situated on a branch of the Silk Road called the "Buddhist Silk Road." Many of the Pamirs' archeological monuments and sacred sites are located in Ishkashim. Fourteen kilometers from the district center in Namatgut village sits one of oldest fortress of the Western Pamirs, Qahqah, dated from the 3rd century BC. Another fortress of the same functionality and name is situated on a rocky slope 76 kilometers from Namatgut near Yamchun village. High walls, towers, and residential and economic locations enclosed the fortress.

Yamg is another famous place among the Wakhan villages. A main attraction of the village is Sufi Muborakqadam's mausoleum. This Sufi was a scholar, poet, and theologian and manufactured musical instruments as well, among which are the most famous "balandmuqom" and "balandzughom". Located next to his mausoleum is a vertical stone with a hole through the center that was used by the Sufi to determine the calendar and various celebrations.

Numerous natural hot springs, or chashmas, exist throughout Ishkashim and are known for healing the body and spirit of visitors. Closest to Khorog, the administrative center of GBAO, is Garmchashma, which translates simply to "hot spring." This site features a spectacular outdoor pool where visitors can soak in mineral rich water under the stars. Another chashma called Auj has mineral rich water that is good for eyes and is situated close to the administrative center of Ishkahsim. Visitors to this spring hold their face in front of the flowing spring and let the water cleanse their eyes. Bibi Fatima is a spring known for bestowing fertility as well as granting wishes. It is located inside a huge rock alcove near the Qahqah fortress in Yamchun.